Frankfurt International Airport (FRA): Approximate driving time is 15 minutes.

From all directions: Follow the sign to the Frankfurt City center - main train station, and park your car in the underground car park, which is on the north side of the station. Come out to the front of the station where you will see that the main entrance is directly opposite to the start of the Kaiser Street. You simply go straight along Kaiser Street, and after 100 yards on the left side you will see the Hotel Kaiserhof (approximately 3 minutes by foot).